PeriGuard Antimicrobial Protectant Barrier Cream 3-1/2 oz Tube PeriGuard is a specially formulated antimicrobial barrier ointment with Zinc Oxide. PeriGuard also contains the antimicrobial agent Chloroxylenol which makes it a perfect candidate for residents prone to urinary tract infections. PeriGuard is also enriched with vitamins A, D and E. PeriGuard leaves skin soft and supple. It leaves no heavy hard to remove residue, which allows skin to breath and heal quickly. Use to treat diaper rash, dry skin or in a prevention program.